MOST PUBLISHED META-REGRESSION ANALYSES BASED ON AGGREGATE DATA SUFFER FROM METHODOLOGICAL PITFALLS: A META-EPIDEMIOLOGICAL STUDY

Most published meta-regression analyses based on aggregate data suffer from methodological pitfalls: a meta-epidemiological study

Abstract Background Due to clinical and methodological diversity, clinical studies included in meta-analyses often differ in ways that lead to differences in treatment effects across studies.Meta-regression analysis is generally recommended to explore associations between study-level characteristics and treatment effect, however, three key pitfalls

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Genomic Structure, Evolutionary Origins, and Reproductive Function of a Large Amplified Intrinsically Disordered Protein-Coding Gene on the X Chromosome (Laidx) in Mice

Mouse sex chromosomes are enriched for co-amplified gene families, present in tens to hundreds of copies.Co-amplification of Slx/Slxl1 on the X chromosome and Sly on the Y chromosome are involved in dose-dependent meiotic drive, however the role of other co-amplified genes remains poorly understood.Here we demonstrate that the co-amplified gene fam

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Indigenous Knowledge and the Convention on Biological Diversity

Abstract Australia is rich in biological diversity and Indigenous Australians hold substantial knowledge SERRATIOPEPTIDASE 90 about how to care for and utilise a diverse range of plants and other biological elements which occur here.Australia has a specific 3D TPU Parts set of legal and policy obligations arising from its ratification of the Conven

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